Wednesday, 4 September 2013

The Challenge

Here is the challenge to Ginger Taylor and her army of lack brains. Show me and other readers how these reports are wrong, and do it by addressing the responses and not the people who wrote them. If you can't or won't then it would be clear that the responses are accurate and the reports have to be noted as not proving any sort of link between vaccines and Autism. It's black and white with no grey areas.

Elevated maternal C-reactive protein and autism in a national birth cohort.

Correct citation: Brown AS, Sourander A, Hinkka-Yli-Salomäki S, McKeague IW, Sundvall J, Surcel HM. Elevated maternal C-reactive protein and autism in a national birth cohort. Mol Psychiatry. 2013 Jan 22. doi: 10.1038/mp.2012.197. [Epub ahead of print]

This study does not address vaccines.

[needs additional attention]

Inflammatory Responses to Trivalent Influenza Virus Vaccine Among Pregnant Women

Correct citation: Christian LM, Iams JD, Porter K, Glaser R. Inflammatory responses to trivalent influenza virus vaccine among pregnant women. Vaccine. 2011 Nov 8;29(48):8982-7. doi: 10.1016/j.vaccine.2011.09.039. Epub 2011 Sep 22.

Two subsequent studies, listed below, have confirmed the safety of trivalent influenza virus vaccines for pregnant women and the children whose mothers were vaccinated during pregnancy.

Nordin JD, Kharbanda EO, Benitez GV, Nichol K, Lipkind H, Naleway A, Lee GM, Hambidge S, Shi W, Olsen A. Maternal safety of trivalent inactivated influenza vaccine in pregnant women. Obstet Gynecol. 2013 Mar;121(3):519-25. doi: 10.1097/AOG.0b013e3182831b83.

Conlin AM, Bukowinski AT, Sevick CJ, DeScisciolo C, Crum-Cianflone NF. Safety of the pandemic H1N1 influenza vaccine among pregnant U.S. military women and their newborns. Obstet Gynecol. 2013 Mar;121(3):511-8. doi: 10.1097/AOG.0b013e318280d64e.

Autism Spectrum Disorders in Relation to Distribution of Hazardous Air Pollutants in the SF Bay Area

Correct citation: Windham GC, Zhang L, Gunier R, Croen LA, Grether JK. Autism spectrum disorders in relation to distribution of hazardous air pollutants in the san francisco bay area. Environ Health Perspect. 2006 Sep;114(9):1438-44.

This study does not address vaccines.

[needs additional attention]

Thimerosal and autism? A plausible hypothesis that should not be dismissed.

Correct citation: Blaxill MF, Redwood L, Bernard S. Thimerosal and autism? A plausible hypothesis that should not be dismissed. Med Hypotheses. 2004;62(5):788-94.

The concerns about thimerosal have been addressed with epidemiological studies, and dismissed. The concerns about thimerosal have been given a thorough airing in the Vaccine Injury Compensation Program legal hearings (Autism Omnibus) and have been found to be baseless.

Slow CCL2-dependent translocation of biopersistent particles from muscle to brain

Correct citation: Khan Z, Combadière C, Authier FJ, Itier V, Lux F, Exley C, Mahrouf-Yorgov M, Decrouy X, Moretto P, Tillement O, Gherardi RK, Cadusseau J. Slow CCL2-dependent translocation of biopersistent particles from muscle to brain. BMC Med. 2013 Apr 4;11:99. doi: 10.1186/1741-7015-11-99.

This paper assumes that ‘Shoenfeld syndrome” or "Autoimmune (Auto-inflammatory) Syndrome Induced by Adjuvants” (ASIA) is a real thing. It has not yet been verified.

I have asked the Science Based Medicine folk to address

[needs additional attention]

The rise in autism and the role of age at diagnosis.

Correct citation: Hertz-Picciotto I, Delwiche L. The rise in autism and the role of age at diagnosis. Epidemiology. 2009 Jan;20(1):84-90. doi: 10.1097/EDE.0b013e3181902d15.

“Autism incidence in California shows no sign yet of plateauing. Younger ages at diagnosis, differential migration, changes in diagnostic criteria, and inclusion of milder cases do not fully explain the observed increases.”

Evidently, according to Taylor, that means that vaccine must account for the observed increases, while disregarding significant changes in demographic data, such as maternal and paternal age at first childbirth.

It is curious that Taylor does not include the other 18 papers on autism in which Hertz-Picciotto has been a contributing author

http://www.ncbi.nlm.nih.gov/pubmed?term=((Hertz-Picciotto%20I%5BAuthor%5D)%20AND%20(%222009%2F1%2F1%22%5BDate%20-%20Publication%5D%20%3A%20%223000%22%5BDate%20-%20Publication%5D))%20AND%20autism%5BMeSH%20Major%20Topic%5D